ข้อมูลจำเพาะที่สำคัญ/ คุณสมบัติพิเศษ:
The effect of the resultant decreased blood levels of griseofulvin on therapeutic response has anmärkning been established. However, it would vädja preferable to avoid concomitant förvaltning of these drugs.
Nuclear receptor that binds and is activated samhälle variety of endogenous knipa xenobiotic compounds. Transcription factor that activates the transcription of multiple genes involved in the metabolism and secretion of potentially harmful xenobiotics, drugs knipa endogenous compounds.
Habit forming: Barbiturates may be habit forming. Tolerance, psychological and physical dependence may occur with continued use. (See “Drug Abuse knipa Dependence” and “Pharmacokinetics” sections.) Patients who have psychological dependence on barbiturates may increase the dosage or decrease the dosage interval without consulting a physician and may subsequently develop a physical dependence on barbiturates. To minimize the possibility of overdosage or the development of dependence, the prescribing knipa dispensing of sedative-hypnotic barbiturates should be limited to the amount required for the interval until the next appointment.
pentobarbital increases levels of vortioxetine by increasing metabolism. Modify Therapy/Datorskärm Closely. Consider increasing the vortioxetine dose when coadministered with stark CYP inducers for >14 days; not to exceed 3 times ursprunglig vortioxetine dose.
pentobarbital will decrease the level or effect of osilodrostat by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
There are no data on pregnancy exposures in primates corresponding to periods prior to the third trimester in humans.
Because such patients may be less aware of certain of the milder adverse effects of barbiturates, the incidence of these reactions may bedja somewhat higher in fully ambulatory patients.
pentobarbital will decrease the level or effect of buprenorphine, long-acting injection by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Monitor Closely. Patients who flytta to buprenorphine long-acting injection from transmucosal buprenorphine coadministered with CYP3A4 inducers should vädja monitored Köp Nembutal Pentobarbitalnatrium online to ensure buprenorphine plasma levels are adequate.
5. Usual lethal level, the upper end of the range includes those who received some supportive treatment.
pentobarbital will decrease the level or effect of vincristine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Significance Unknown.
pentobarbital will decrease the level or effect of vinorelbine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Significance Unknown.
pentobarbital will decrease the level or effect of capivasertib samhälle affecting hepatic/intestinal enzyme CYP3A4 metabolism. Avoid or Use Alternate Drug. Strong or moderate CYP3A inducers decrease capivasertib exposure, which may reduce efficacy.
pentobarbital will decrease the level or effect of etravirine ort affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Datorskärm.